Pharos : Ligand Details - YWJM3VU7NHGW

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Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

Name: Minalrestat

PubChem: 190816

ChEMBL: CHEMBL273910

LyCHI: YWJM3VU7NHGW

Target Activities

Explore Associated and Predicted Targets

AKR1B1

Tclin

Aldose reductase

4 Activities

Items per page:

1 – 4 of 4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	7.91		J. Med. Chem., (1994) 37:13:2043	8027986

IC50	7.6		Bioorg. Med. Chem., (2010) 18:7:2485	20304656

IC50	7.16		Bioorg. Med. Chem., (2008) 16:6:3245	18165015

IC50	7.14		Bioorg. Med. Chem., (2007) 15:24:7865	17870536

AKR1B10

Tchem

Aldo-keto reductase family 1 member B10

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.13		Bioorg. Med. Chem., (2010) 18:7:2485	20304656

AKR1A1

Tchem

Alcohol dehydrogenase [NADP(+)]

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	8.17		Bioorg. Med. Chem., (2010) 18:7:2485	20304656