CHEMBL199824
Ligand Summary
Name: [O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]butyl}-4-methyl-2H-[1,2,4]triazine-3,5-dione
PubChem: 11676174
ChEMBL: CHEMBL199824
LyCHI: YTCUFLB4Z3DD
Target Activities
HTR1A
5-hydroxytryptamine receptor 1A
3 Activities
DRD2
D(2) dopamine receptor
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 7.66 | J. Med. Chem., (2006) 49:1:125 | ||||
DRD3
D(3) dopamine receptor
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 7.2 | J. Med. Chem., (2006) 49:1:125 | ||||
DRD4
D(4) dopamine receptor
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 8.07 | J. Med. Chem., (2006) 49:1:125 | ||||
SIGMAR1
Sigma non-opioid intracellular receptor 1
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 6.32 | J. Med. Chem., (2006) 49:1:125 | ||||
HTR2A
5-hydroxytryptamine receptor 2A
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 7.38 | J. Med. Chem., (2006) 49:1:125 | ||||
HTR2C
5-hydroxytryptamine receptor 2C
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 7 | J. Med. Chem., (2006) 49:1:125 | ||||
SLC6A3
Sodium-dependent dopamine transporter
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 6.39 | J. Med. Chem., (2006) 49:1:125 | ||||
HTR7
5-hydroxytryptamine receptor 7
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 8.04 | J. Med. Chem., (2006) 49:1:125 | ||||
ADRB2
Beta-2 adrenergic receptor
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 7.22 | J. Med. Chem., (2006) 49:1:125 | ||||
ADRA2C
Alpha-2C adrenergic receptor
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 7.62 | J. Med. Chem., (2006) 49:1:125 | ||||