CHEMBL478629
Ligand Summary
Name: [4-(2-piperidin-1-yl-ethoxy)-phenyl])-3-pyridin-4-yl-pyrrazolo[1,5-a]-pyrimidine
PubChem: 11524144
Guide to Pharmacology: 4907
ChEMBL: CHEMBL478629
LyCHI: YS5RSZQDF5R3
Target Activities
Items per page:
10
1 – 10 of 10
KDR
Vascular endothelial growth factor receptor 2
5 Activities
Items per page:
1 – 5 of 5
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.6 | None, (2015) None:None:None | ||||
IC50 | 7.6 | None, (2015) None:None:None | ||||
IC50 | 7.66 | Bioorg. Med. Chem. Lett., (2013) 23:11:3248 | ||||
IC50 | 8.4 | Bioorg. Med. Chem. Lett., (2010) 20:22:6394 | ||||
IC50 | 8.39999962 | |||||
EPHA2
Ephrin type-A receptor 2
2 Activities
LCK
Tyrosine-protein kinase Lck
2 Activities
MKNK1
MAP kinase-interacting serine/threonine-protein kinase 1
2 Activities
SRC
Proto-oncogene tyrosine-protein kinase Src
2 Activities
FLT1
Vascular endothelial growth factor receptor 1
2 Activities
YES1
Tyrosine-protein kinase Yes
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.53 | Bioorg. Med. Chem. Lett., (2013) 23:15:4398 | ||||
BMP4
Bone morphogenetic protein 4
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.37 | Bioorg. Med. Chem. Lett., (2008) 18:15:4388 | ||||
FLT3
Receptor-type tyrosine-protein kinase FLT3
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 9 | |||||
RPS6KA1
Ribosomal protein S6 kinase alpha-1
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.67999983 | |||||