CHEMBL445813
Ligand Summary
Name: AT-7519
PubChem: 11338033
Guide to Pharmacology: 5662
ChEMBL: CHEMBL445813
LyCHI: XWLJRD43W5DV
Target Activities
CDK4
Cyclin-dependent kinase 4
3 Activities
CDK9
Cyclin-dependent kinase 9
2 Activities
CDK2
Cyclin-dependent kinase 2
2 Activities
CDK17
Cyclin-dependent kinase 17
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 9.02 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
CDK16
Cyclin-dependent kinase 16
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 8.96 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
CDK13
Cyclin-dependent kinase 13
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 8.49 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
CASK
Peripheral plasma membrane protein CASK
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 7.62 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
CDK11A
Cyclin-dependent kinase 11A
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 8.28 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
CDK11B
Cyclin-dependent kinase 11B
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 8.08 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
GSK3B
Glycogen synthase kinase-3 beta
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 7.96 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
GSK3A
Glycogen synthase kinase-3 alpha
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 7.64 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
CDK7
Cyclin-dependent kinase 7
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 8.55 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
CDK14
Cyclin-dependent kinase 14
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 7.8 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
CDKL5
Cyclin-dependent kinase-like 5
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 8.59 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
ICK
Serine/threonine-protein kinase ICK
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 8.08 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
CDK18
Cyclin-dependent kinase 18
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 7.85 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
CDK1
Cyclin-dependent kinase 1
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.67999983 | |||||
CDK5
Cyclin-dependent-like kinase 5
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.88999987 | |||||
CDK6
Cyclin-dependent kinase 6
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.76999998 | |||||