Pharos : Ligand Details

Target Activities

Explore Associated and Predicted Targets

CDK9

Tchem

Cyclin-dependent kinase 9

4 Activities

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1 – 4 of 4

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
IC50	8		19174555

Kd	8.24	Nat. Biotechnol., (2011) 29:11:1046	22037378

Kd	8.15	Science, (2017) 358:6367:None	29191878

IC50	8	Eur J Med Chem, (2017) 142:None:424	28911822

CDK4

Tclin

Cyclin-dependent kinase 4

3 Activities

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1 – 3 of 3

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
IC50	7		19174555

Kd	7.92	Nat. Biotechnol., (2011) 29:11:1046	22037378

Kd	7.7	Nat. Biotechnol., (2011) 29:11:1046	22037378

CDK2

Tchem

Cyclin-dependent kinase 2

2 Activities

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1 – 2 of 2

Activity Type	Activity Value -log(M)	Publications (PubMed IDs)
IC50	7.33	19174555

Kd	7.52	22037378

CDK17

Tchem

Cyclin-dependent kinase 17

2 Activities

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1 – 2 of 2

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
Kd	9.02	Nat. Biotechnol., (2011) 29:11:1046	22037378

Kd	8.15	Science, (2017) 358:6367:None	29191878

CDK16

Tchem

Cyclin-dependent kinase 16

2 Activities

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1 – 2 of 2

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
Kd	8.96	Nat. Biotechnol., (2011) 29:11:1046	22037378

Kd	8.1	Science, (2017) 358:6367:None	29191878

CDK1

Tchem

Cyclin-dependent kinase 1

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.68			19174555

CDK5

Tchem

Cyclin-dependent-like kinase 5

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	7.89			19174555

CDK6

Tclin

Cyclin-dependent kinase 6

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.77			19174555

GSK3A

Tclin

Glycogen synthase kinase-3 alpha

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	7.64		Nat. Biotechnol., (2011) 29:11:1046	22037378

CDK7

Tchem

Cyclin-dependent kinase 7

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	8.55		Nat. Biotechnol., (2011) 29:11:1046	22037378

CLK3

Tchem

Dual specificity protein kinase CLK3

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	7.92		Science, (2017) 358:6367:None	29191878

GSK3B

Tclin

Glycogen synthase kinase-3 beta

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	7.96		Nat. Biotechnol., (2011) 29:11:1046	22037378

CDK18

Tchem

Cyclin-dependent kinase 18

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	7.85		Nat. Biotechnol., (2011) 29:11:1046	22037378

CDK11A

Tchem

Cyclin-dependent kinase 11A

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	8.28		Nat. Biotechnol., (2011) 29:11:1046	22037378

CDK11B

Tchem

Cyclin-dependent kinase 11B

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	8.08		Nat. Biotechnol., (2011) 29:11:1046	22037378

CDK14

Tchem

Cyclin-dependent kinase 14

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	7.8		Nat. Biotechnol., (2011) 29:11:1046	22037378

CDKL5

Tchem

Cyclin-dependent kinase-like 5

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	8.59		Nat. Biotechnol., (2011) 29:11:1046	22037378

ICK

Tchem

Serine/threonine-protein kinase ICK

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	8.08		Nat. Biotechnol., (2011) 29:11:1046	22037378

CASK

Tchem

Peripheral plasma membrane protein CASK

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	7.62		Nat. Biotechnol., (2011) 29:11:1046	22037378

CDK13

Tchem

Cyclin-dependent kinase 13

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	8.49		Nat. Biotechnol., (2011) 29:11:1046	22037378