Pharos : Ligand Details - XWCC7X1A3Z8B

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Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

Name: 2,4-pyridine dicarboxylic acid

PubChem: 10365

Guide to Pharmacology: 8744

ChEMBL: CHEMBL316034

LyCHI: XWCC7X1A3Z8B

Target Activities

Explore Associated and Predicted Targets

KDM4C

Tchem

Lysine-specific demethylase 4C

4 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	8.66		J. Med. Chem., (2016) 59:4:1580	26699912

IC50	6.73		J. Med. Chem., (2016) 59:4:1580	26699912

IC50	6.28		J. Med. Chem., (2016) 59:4:1580	26699912

IC50	6.21		J. Med. Chem., (2016) 59:4:1580	26699912

ASPH

Tchem

Aspartyl/asparaginyl beta-hydroxylase

4 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	7.7		Bioorg Med Chem, (2020) 28:20.0:115675	33069066

IC50	7.7		Bioorg Med Chem, (2020) 28:20.0:115675	33069066

IC50	7.52		Bioorg Med Chem, (2020) 28:20.0:115675	33069066

IC50	7		Bioorg Med Chem, (2020) 28:20.0:115675	33069066

KDM4A

Tchem

Lysine-specific demethylase 4A

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.15			18942826

IC50	6.16		J. Med. Chem., (2008) 51:22:7053	18942826

KDM4E

Tchem

Lysine-specific demethylase 4E

1 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	5.85			18942826

EGLN1

Tclin

Egl nine homolog 1

1 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	6.38		J. Med. Chem., (2013) 56:2:547	23234607

KDM5C

Tchem

Lysine-specific demethylase 5C

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.3		MedChemComm, (2014) 5:12:1879	26682034

KDM5A

Tchem

Lysine-specific demethylase 5A

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.12		J. Med. Chem., (2016) 59:4:1580	26699912