momelotinib
Ligand Summary
Name: momelotinib
PubChem: 25062766
Guide to Pharmacology: 7791
ChEMBL: CHEMBL1078178
LyCHI: XMBWANRVDM8D
Target Activities
JAK1
Tyrosine-protein kinase JAK1
3 Activities
JAK2
Tyrosine-protein kinase JAK2
3 Activities
ACVR1
Activin receptor type-1
2 Activities
Items per page:
1 – 2 of 2
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.1 | None, (2016) None:None:None | ||||
Kd | 7.6 | None, (2016) None:None:None | ||||
JAK3
Tyrosine-protein kinase JAK3
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.81 | |||||
AAK1
AP2-associated protein kinase 1
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 8.4 | Science, (2017) 358:6367:None | ||||
BMPR1B
Bone morphogenetic protein receptor type-1B
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 7.72 | None, (2016) None:None:None | ||||
Q6ZSR9
Uncharacterized protein FLJ45252
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 8.52 | Science, (2017) 358:6367:None | ||||
OPA1
Dynamin-like 120 kDa protein, mitochondrial
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 6.15 | Science, (2017) 358:6367:None | ||||