CHEMBL1089843
Ligand Summary
Name: (R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-dioxoisoindolin-2-yl)-N-hydroxybutanamide
PubChem: 45378253
ChEMBL: CHEMBL1089843
LyCHI: XKG99FURTZ3W
Target Activities
ADAM17
Disintegrin and metalloproteinase domain-containing protein 17
10 Activities
Items per page:
1 – 10 of 10
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 9.15 | J. Med. Chem., (2010) 53:6:2622 | ||||
IC50 | 8.37 | J. Med. Chem., (2010) 53:6:2622 | ||||
IC50 | 7.82 | J. Med. Chem., (2010) 53:6:2622 | ||||
IC50 | 7.29 | J. Med. Chem., (2010) 53:6:2622 | ||||
IC50 | 7.14 | J. Med. Chem., (2010) 53:6:2622 | ||||
IC50 | 7.01 | J. Med. Chem., (2010) 53:6:2622 | ||||
IC50 | 6.55 | J. Med. Chem., (2010) 53:6:2622 | ||||
IC50 | 6.26 | J. Med. Chem., (2010) 53:6:2622 | ||||
IC50 | 6.12 | J. Med. Chem., (2010) 53:6:2622 | ||||
IC50 | 6.1 | J. Med. Chem., (2010) 53:6:2622 | ||||
MMP14
Matrix metalloproteinase-14
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.37 | J. Med. Chem., (2010) 53:6:2622 | ||||
MMP2
72 kDa type IV collagenase
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.38 | J. Med. Chem., (2010) 53:6:2622 | ||||
MMP9
Matrix metalloproteinase-9
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.46 | J. Med. Chem., (2010) 53:6:2622 | ||||
MMP1
Interstitial collagenase
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.46 | J. Med. Chem., (2010) 53:6:2622 | ||||
ADAM10
Disintegrin and metalloproteinase domain-containing protein 10
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.72 | J. Med. Chem., (2010) 53:6:2622 | ||||