Obatoclax
Ligand Summary
Target Activities
MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1
2 Activities
BCL2A1
Bcl-2-related protein A1
2 Activities
BAD
Bcl2-associated agonist of cell death
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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Ki | 6 | Proc. Natl. Acad. Sci. U.S.A., (2007) 104:49:19512 | ||||
BCL2L1
Bcl-2-like protein 1
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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EC50 | 6.05 | Eur. J. Med. Chem., (2012) 57:None:112 | ||||
BCL2L2
Bcl-2-like protein 2
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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Ki | 6 | Proc. Natl. Acad. Sci. U.S.A., (2007) 104:49:19512 | ||||
BCL2
Apoptosis regulator Bcl-2
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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EC50 | 6.52 | Eur. J. Med. Chem., (2012) 57:None:112 | ||||
BCL2L10
Bcl-2-like protein 10
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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Ki | 6 | Proc. Natl. Acad. Sci. U.S.A., (2007) 104:49:19512 | ||||