Pharos: Illuminating the Druggable Genome

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Ligand Summary

Ligand Structure

chemical structure image

Synonyms & Links

NCATS Inxight: Drugs: 136053677,135567128

Name: 2-((1-(Cyclohexylmethyl)-1H-pyrazol-4-yl)oxy)pyrido[3,4-d]-pyrimidin-4(3H)-one

PubChem: 136053677,135567128

ChEMBL: CHEMBL3771198,CHEMBL3771180

LyCHI: WTSM5NPBHR81

Target Activities

Items per page:

10

1 – 5 of 5

KDM4A

Tchem

Lysine-specific demethylase 4A

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.2		J. Med. Chem., (2016) 59:4:1370	26771203

IC50	6.2		J. Med. Chem., (2016) 59:4:1370	26771203

KDM5C

Tchem

Lysine-specific demethylase 5C

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	7.1		J. Med. Chem., (2016) 59:4:1370	26771203

IC50	7.2		J. Med. Chem., (2016) 59:4:1370	26771203

KDM4E

Tchem

Lysine-specific demethylase 4E

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.3		J. Med. Chem., (2016) 59:4:1370	26771203

IC50	6.3		J. Med. Chem., (2016) 59:4:1370	26771203

KDM4D

Tchem

Lysine-specific demethylase 4D

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.4		J. Med. Chem., (2016) 59:4:1370	26771203

IC50	6.4		J. Med. Chem., (2016) 59:4:1370	26771203

KDM4C

Tchem

Lysine-specific demethylase 4C

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.2		J. Med. Chem., (2016) 59:4:1370	26771203

IC50	6.3		J. Med. Chem., (2016) 59:4:1370	26771203