CHEMBL129857
Ligand Summary
Name: 1-(5-methoxy-2-(thiophen-2-yl)quinazolin-4-ylamino)-3-methyl-1H-pyrrole-2,5-dione
PubChem: 9820526
ChEMBL: CHEMBL129857
LyCHI: WD391N7NADVH
Target Activities
IKBKB
Inhibitor of nuclear factor kappa-B kinase subunit beta
2 Activities
JUN
Transcription factor AP-1
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.1 | J. Med. Chem., (2014) 57:16:6930 | ||||
RELA
Transcription factor p65
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
EC50 | 6.42 | Bioorg. Med. Chem. Lett., (2009) 19:4:1191 | ||||