Pharos : Ligand Details - VUNAPND3VJVB

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Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

Name: MK-5108

PubChem: 24748204

Guide to Pharmacology: 8061

ChEMBL: CHEMBL3182444

LyCHI: VUNAPND3VJVB

Target Activities

Explore Associated and Predicted Targets

AURKA

Tchem

Aurora kinase A

2 Activities

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1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	10.19			20053775

Kd	10		Science, (2017) 358:6367:None	29191878

AURKB

Tchem

Aurora kinase B

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	7.85			20053775

AURKC

Tchem

Aurora kinase C

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	7.92			20053775

JAK2

Tclin

Tyrosine-protein kinase JAK2

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	7.6		Science, (2017) 358:6367:None	29191878

IRAK3

Tchem

Interleukin-1 receptor-associated kinase 3

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	7.62		Science, (2017) 358:6367:None	29191878

BCR

Tclin

Breakpoint cluster region protein

1 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	7.96		Science, (2017) 358:6367:None	29191878

TNK1

Tchem

Non-receptor tyrosine-protein kinase TNK1

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	8.22		Science, (2017) 358:6367:None	29191878

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