Pharos : Ligand Details - VH6GPWWYZ7F1

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Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

Name: ZD7288

PubChem: 123984

PubChem: 9796088

Guide to Pharmacology: 2359

ChEMBL: CHEMBL2052019

LyCHI: VH6GPWWYZ7F1

Target Activities

Explore Associated and Predicted Targets

HCN1

Tclin

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

2 Activities

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1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	4.7			16043489

IC50	6.8		Bioorg. Med. Chem. Lett., (2011) 21:18:5197	21824780

HCN4

Tclin

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	4.7			16043489

IC50	7.5		Bioorg. Med. Chem. Lett., (2011) 21:18:5197	21824780

HCN2

Tclin

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	4.4			16043489

HCN3

Tclin

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	4.5			16043489