Pharos : Ligand Details - VFAMQ9QFTB5D

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Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

Name: 3-[3-tert-Butylsulfanyl-1-[4-(6-ethoxypyridin-2-yl)benzyl]-5-(5-methylpyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethylpropionic acid

PubChem: 56850523

ChEMBL: CHEMBL1922661

LyCHI: VFAMQ9QFTB5D

Target Activities

ALOX5AP

Tchem

Arachidonate 5-lipoxygenase-activating protein

3 Activities

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1 – 3 of 3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	9.22		J. Med. Chem., (2011) 54:23:8013	22059882

IC50	8.85		J. Med. Chem., (2011) 54:23:8013	22059882

IC50	6.25		J. Med. Chem., (2011) 54:23:8013	22059882

PTGS1

Tclin

Prostaglandin G/H synthase 1

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.21		J. Med. Chem., (2011) 54:23:8013	22059882