Pharos : Ligand Details

Target Activities

Explore Associated and Predicted Targets

PLA2G2A

Tchem

Phospholipase A2, membrane associated

10 Activities

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1 – 10 of 10

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
IC50	8.05		8978844 10027849

IC50	8.15		8978844

IC50	8.15	J. Med. Chem., (1996) 39:26:5159	8978844

IC50	8.15	J. Med. Chem., (2005) 48:3:893	15689175

IC50	8.05	J. Med. Chem., (1996) 39:26:5159	8978844

IC50	7.92	ACS Med Chem Lett, (2018) 9:7:594	30034585

IC50	7.89	J. Med. Chem., (2005) 48:3:893	15689175

IC50	7.55	ACS Med Chem Lett, (2016) 7:10:884	27774123

IC50	6.9	J. Med. Chem., (2006) 49:10:2858	16686528

IC50	6.9	J. Med. Chem., (2008) 51:15:4708	18605714

PLA2G6

Tchem

85/88 kDa calcium-independent phospholipase A2

7 Activities

Items per page:

1 – 7 of 7

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
IC50	7.25	J Med Chem, (2019) 62:4:1999	30615445

IC50	6.98	J Med Chem, (2019) 62:4:1999	30615445

IC50	6.88	J Med Chem, (2019) 62:4:1999	30615445

IC50	6.6	J Med Chem, (2019) 62:4:1999	30615445

IC50	6.48	J Med Chem, (2019) 62:4:1999	30615445

IC50	6.23	J Med Chem, (2019) 62:4:1999	30615445

IC50	6.22	J Med Chem, (2019) 62:4:1999	30615445

PLA2G10

Tchem

Group 10 secretory phospholipase A2

6 Activities

Items per page:

1 – 6 of 6

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
IC50	7.39	ACS Med Chem Lett, (2018) 9:7:594	30034585

IC50	7.39	ACS Med Chem Lett, (2016) 7:10:884	27774123

IC50	7.12	J. Med. Chem., (2006) 49:10:2858	16686528

IC50	7.12	J. Med. Chem., (2008) 51:15:4708	18605714

IC50	6.97	Bioorg. Med. Chem. Lett., (2014) 24:22:5251	25316315

IC50	6.82	ACS Med Chem Lett, (2018) 9:7:594	30034585

PLA2G5

Tchem

Calcium-dependent phospholipase A2

3 Activities

Items per page:

1 – 3 of 3

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
IC50	6.91	ACS Med Chem Lett, (2018) 9:7:594	30034585

IC50	6.3	J. Med. Chem., (2006) 49:10:2858	16686528

IC50	6.3	J. Med. Chem., (2008) 51:15:4708	18605714

PLA2G1B

Tchem

Phospholipase A2

3 Activities

Items per page:

1 – 3 of 3

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
IC50	6.64	J. Med. Chem., (1996) 39:26:5159	8978844

IC50	6.12	J. Med. Chem., (2006) 49:10:2858	16686528

IC50	6.12	J. Med. Chem., (2008) 51:15:4708	18605714

PLA2G2E

Tchem

Group IIE secretory phospholipase A2

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
IC50	7.3	J. Med. Chem., (2006) 49:10:2858	16686528

IC50	7.3	J. Med. Chem., (2008) 51:15:4708	18605714

PLA2G2F

Tchem

Group IIF secretory phospholipase A2

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.89		J. Med. Chem., (2008) 51:15:4708	18605714

PLA2G2D

Tchem

Group IID secretory phospholipase A2

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	7.22		J. Med. Chem., (2008) 51:15:4708	18605714