CHEMBL2059435
Ligand Summary
Name: 2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((2S,3S)-2-hydroxypentan-3-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid
PubChem: 56965957
ChEMBL: CHEMBL2059435
LyCHI: UVUBHCF6XD8V
Target Activities
MDM2
E3 ubiquitin-protein ligase Mdm2
5 Activities
Items per page:
1 – 5 of 5
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 9.4 | J. Med. Chem., (2012) 55:11:4934 | ||||
Kd | 9.4 | J. Med. Chem., (2012) 55:11:4936 | ||||
Kd | 9.4 | J. Med. Chem., (2014) 57:4:1454 | ||||
IC50 | 8.96 | J. Med. Chem., (2014) 57:4:1454 | ||||
IC50 | 8.39 | J. Med. Chem., (2014) 57:4:1454 | ||||
TP53
Cellular tumor antigen p53
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.12 | J. Med. Chem., (2012) 55:11:4936 | ||||