Ro 40-6055
Ligand Summary
Name: Ro 40-6055
PubChem: 2126
Guide to Pharmacology: 2647
ChEMBL: CHEMBL69367
LyCHI: UKXRDHPA4RX9
Target Activities
RARA
Retinoic acid receptor alpha
8 Activities
Items per page:
1 – 8 of 8
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
EC50 | 9.52 | |||||
EC50 | 9.52 | Bioorg. Med. Chem. Lett., (2009) 19:2:489 | ||||
EC50 | 8.7 | Bioorg. Med. Chem. Lett., (2002) 12:21:3145 | ||||
EC50 | 8.4 | J. Med. Chem., (2011) 54:3:788 | ||||
Kd | 7.44 | Bioorg. Med. Chem. Lett., (2002) 12:21:3145 | ||||
Kd | 7.44 | J. Med. Chem., (1996) 39:16:3035 | ||||
IC50 | 7.39 | J. Med. Chem., (2000) 43:3:409 | ||||
EC50 | 7.1 | J. Med. Chem., (2009) 52:6:1540 | ||||
RARB
Retinoic acid receptor beta
7 Activities
Items per page:
1 – 7 of 7
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
EC50 | 8.07 | |||||
EC50 | 8.07 | Bioorg. Med. Chem. Lett., (2009) 19:2:489 | ||||
EC50 | 8.05 | Bioorg. Med. Chem. Lett., (2002) 12:21:3145 | ||||
EC50 | 7.7 | J. Med. Chem., (2005) 48:24:7517 | ||||
EC50 | 7.7 | J. Med. Chem., (2009) 52:6:1540 | ||||
EC50 | 7.3 | J. Med. Chem., (2005) 48:24:7517 | ||||
EC50 | 7.3 | J. Med. Chem., (2009) 52:6:1540 | ||||
RARG
Retinoic acid receptor gamma
4 Activities
Items per page:
1 – 4 of 4
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
EC50 | 7.89 | |||||
EC50 | 7.89 | Bioorg. Med. Chem. Lett., (2009) 19:2:489 | ||||
EC50 | 7.72 | Bioorg. Med. Chem. Lett., (2002) 12:21:3145 | ||||
EC50 | 7.6 | J. Med. Chem., (2009) 52:6:1540 | ||||