US9458145, 1020-18
Ligand Summary
Target Activities
BRD4
Bromodomain-containing protein 4
13 Activities
Items per page:
1 – 10 of 13
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 8.89 | Bioorg Med Chem, (2019) 27:3:457 | ||||
Kd | 8.55 | Bioorg Med Chem, (2019) 27:3:457 | ||||
Kd | 8.54 | Bioorg Med Chem, (2019) 27:3:457 | ||||
Kd | 8.49 | Bioorg Med Chem, (2019) 27:3:457 | ||||
Ki | 8.42 | Bioorg Med Chem, (2019) 27:3:457 | ||||
Ki | 8.12 | Bioorg Med Chem, (2019) 27:3:457 | ||||
IC50 | 7.84 | None, (2016) None:None:None | ||||
Ki | 7.8 | Bioorg Med Chem, (2019) 27:3:457 | ||||
EC50 | 7.26 | Bioorg Med Chem, (2019) 27:3:457 | ||||
IC50 | 7.11 | None, (2016) None:None:None | ||||
BRD2
Bromodomain-containing protein 2
3 Activities
BRDT
Bromodomain testis-specific protein
3 Activities
BRD3
Bromodomain-containing protein 3
3 Activities
EP300
Histone acetyltransferase p300
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 6.66 | Bioorg Med Chem, (2019) 27:3:457 | ||||
CREBBP
CREB-binding protein
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 6.77 | Bioorg Med Chem, (2019) 27:3:457 | ||||