Synonyms for this ligand, and links to other sources that refer to it.
Visual representation of the ligand, as well as synonyms and links to other information sources.
click for section description and definitions
List of targets within Pharos that are related to this ligand.
Opens the Target List with this set of targets
Hierarchical classifications for this protein from different ontologies.
Expression data from several sources shown as a heatmap of tissues and data sources, and as a shaded anatomogram.
Bar chart summarizing the number of times each residue appears in the sequence. The bars represent the actual counts, while the gold lines represent the expected counts given the frequency of the amino acids in all human genes.
Amino acid sequence of the target protein.
Begin a sequence search with this sequence
The protein sequence aligned with structural and functional annotations, as well as disease variants.
Amino acid sequence, and a detailed sequence structure viewer via the Uniprot Protvista viewer.
A list of related tools that have content for this protein.
Approved drugs that are associated with this target.
Active ligands that are associated with this target.
List of protein-protein interactions associated with this gene. Interactions are reported from Reactome, BioPlex, and StringDB. StringDB score must be above 0.400 to be shown here. Explore on the String-DB website to see lower likelihood targets.
A listing of the nearest upstream and downstream targets from KEGG pathways that have reached the Tclin designation.
Biochemical pathways containing the current target.
Details about predicted viral interactions with this protein, from P-HIPSTer.
A network of biological classes describing the molecular function, cellular locations, and processes genes may carry out, as defined by the Gene Ontology Consortium.
This is a list of diseases associated with this target, compiled by several resources. Each
resource provides different confidence measurements and association values, which are described below.
Genome-wide association studies (GWAS) find associations between phenotypic traits and genes. Target Illumination GWAS Analytics (TIGA) scores and ranks those traits according to a subset of study parameters.
List of targets within Pharos that are related to this target.
Reagents and data sources generated by IDG partner organizations
Orthologous proteins from other species, from OMA, EggNOG, and Inparanoid.
Statistics about the occurence of this target in literature, extracted via text mining. GeneRIFs,and text-mined publications are also displayed. For more details, click the '?' button.
Text-mining extracted GeneRIFs, and publications. For more details, click the '?' button.