CHEMBL1627
Ligand Summary
Name: 4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N-methyl-2,2-diphenylbutanamide
PubChem: 9805944
ChEMBL: CHEMBL1627
LyCHI: U2AMKWQMZLML
Target Activities
OPRM1
Mu-type opioid receptor
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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Ki | 9.22 | J. Med. Chem., (2008) 51:19:6034 | ||||
HRH2
Histamine H2 receptor
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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Ki | 8.77 | J. Med. Chem., (2008) 51:19:6034 | ||||
SLC6A4
Sodium-dependent serotonin transporter
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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Ki | 8.21 | J. Med. Chem., (2008) 51:19:6034 | ||||
ADRA1A
Alpha-1A adrenergic receptor
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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Ki | 8 | J. Med. Chem., (2008) 51:19:6034 | ||||
HRH1
Histamine H1 receptor
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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Ki | 8.38 | J. Med. Chem., (2008) 51:19:6034 | ||||
DRD4
D(4) dopamine receptor
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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Ki | 8.96 | J. Med. Chem., (2008) 51:19:6034 | ||||
ADRA2A
Alpha-2A adrenergic receptor
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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Ki | 9 | J. Med. Chem., (2008) 51:19:6034 | ||||
ADRA2C
Alpha-2C adrenergic receptor
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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Ki | 8.62 | J. Med. Chem., (2008) 51:19:6034 | ||||
HRH3
Histamine H3 receptor
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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Ki | 8.03 | J. Med. Chem., (2008) 51:19:6034 | ||||
ADRA2B
Alpha-2B adrenergic receptor
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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Ki | 8.15 | J. Med. Chem., (2008) 51:19:6034 | ||||