CHEMBL4447805
Ligand Summary
Name: {4-[2-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]-pyrimidin-6-yl)ethoxy]benzoyl}-L-glutamic Acid
PubChem: 155519837
ChEMBL: CHEMBL4447805
LyCHI: TYT31D7FBBHQ
Target Activities
GART
Trifunctional purine biosynthetic protein adenosine-3
2 Activities
SLC46A1
Proton-coupled folate transporter
2 Activities
FOLR1
Folate receptor alpha
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
---|---|---|---|---|---|---|
IC50 | 8.72 | J Med Chem, (2016) 59:17:7856 | ||||
FOLR2
Folate receptor beta
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
---|---|---|---|---|---|---|
IC50 | 8.59 | J Med Chem, (2016) 59:17:7856 | ||||
SLC19A1
Folate transporter 1
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
---|---|---|---|---|---|---|
IC50 | 6.19 | J Med Chem, (2016) 59:17:7856 | ||||