Pharos: Illuminating the Druggable Genome

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Ligand Summary

Ligand Structure

chemical structure image

Synonyms & Links

NCATS Inxight: Drugs: 9855524

Name: 4-Methyl-6-propyl-pyridin-2-ylamine

PubChem: 9855524

ChEMBL: CHEMBL302657

LyCHI: T9U6HCH2JP9W

Target Activities

Items per page:

10

1 – 3 of 3

NOS2

Tchem

Nitric oxide synthase, inducible

3 Activities

Items per page:

1 – 3 of 3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.96		Bioorg. Med. Chem. Lett., (2000) 10:17:1975	10987430

IC50	7.82		Nat. Chem. Biol., (2008) 4:11:700	18849972

IC50	8		J. Med. Chem., (2004) 47:12:3320	15163211

NOS3

Tchem

Nitric oxide synthase, endothelial

3 Activities

Items per page:

1 – 3 of 3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6		Bioorg. Med. Chem. Lett., (2000) 10:17:1975	10987430

IC50	7.3		J. Med. Chem., (2004) 47:12:3320	15163211

IC50	7.47		Nat. Chem. Biol., (2008) 4:11:700	18849972

NOS1

Tchem

Nitric oxide synthase, brain

3 Activities

Items per page:

1 – 3 of 3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	7.05		Bioorg. Med. Chem. Lett., (2000) 10:17:1975	10987430

IC50	7.64		Nat. Chem. Biol., (2008) 4:11:700	18849972

IC50	8		J. Med. Chem., (2004) 47:12:3320	15163211