CHEMBL295467
Ligand Summary
Name: Nisoxetine
PubChem: 4500
Guide to Pharmacology: 4637
ChEMBL: CHEMBL295467
LyCHI: T94MNC9VHVD8
Target Activities
Items per page:
10
1 – 3 of 3
SLC6A2
Sodium-dependent noradrenaline transporter
11 Activities
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1 – 10 of 11
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.7 | Bioorg. Med. Chem. Lett., (2014) 24:15:3234 | ||||
IC50 | 7.75 | J. Med. Chem., (2012) 55:18:8188 | ||||
IC50 | 7.82 | Bioorg. Med. Chem. Lett., (2008) 18:14:4224 | ||||
IC50 | 7.82 | Bioorg. Med. Chem. Lett., (2008) 18:16:4495 | ||||
IC50 | 8.08 | Bioorg. Med. Chem., (2011) 19:1:663 | ||||
IC50 | 8.1 | J. Med. Chem., (2011) 54:15:5283 | ||||
IC50 | 8.1 | Bioorg. Med. Chem. Lett., (2011) 21:5:1434 | ||||
IC50 | 8.22 | Bioorg. Med. Chem. Lett., (2008) 18:18:4929 | ||||
Ki | 8.22 | Bioorg. Med. Chem., (2009) 17:22:7802 | ||||
Ki | 8.8 | J. Med. Chem., (2004) 47:21:5258 | ||||
SLC6A4
Sodium-dependent serotonin transporter
7 Activities
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1 – 7 of 7
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.16 | J. Med. Chem., (2012) 55:18:8188 | ||||
IC50 | 6.16 | Bioorg. Med. Chem. Lett., (2014) 24:15:3234 | ||||
IC50 | 6.16 | ACS Med. Chem. Lett., (2014) 5:9:999 | ||||
IC50 | 6.56 | Bioorg. Med. Chem. Lett., (2008) 18:18:4929 | ||||
Ki | 6.69 | J. Med. Chem., (2004) 47:21:5258 | ||||
IC50 | 7.7 | ACS Med. Chem. Lett., (2014) 5:9:999 | ||||
Ki | 8.85 | J. Med. Chem., (2003) 46:6:925 | ||||
SLC6A3
Sodium-dependent dopamine transporter
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 7.52 | J. Med. Chem., (2003) 46:6:925 | ||||