CHEMBL567341
Ligand Summary
Name: 6-(3,5-Difluorophenylamino)-9-ethyl-9H-purine-2-carbonitrile
PubChem: 44143088
ChEMBL: CHEMBL567341
LyCHI: T5UM5XZRJ8JB
Target Activities
CTSC
Dipeptidyl peptidase 1
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.46 | J. Med. Chem., (2010) 53:1:52 | ||||
CTSS
Cathepsin S
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.8 | J. Med. Chem., (2010) 53:1:52 | ||||
CTSK
Cathepsin K
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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IC50 | 7.63 | J. Med. Chem., (2010) 53:1:52 | ||||
CTSL
Cathepsin L1
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.93 | J. Med. Chem., (2010) 53:1:52 | ||||
CTSZ
Cathepsin Z
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.03 | J. Med. Chem., (2010) 53:1:52 | ||||
CTSH
Pro-cathepsin H
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.9 | J. Med. Chem., (2010) 53:1:52 | ||||
CTSV
Cathepsin L2
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.62 | J. Med. Chem., (2010) 53:1:52 | ||||