CHEMBL4295242
Ligand Summary
Name: 2-(trifluoromethyl)-N-(3,4-dimethoxyphenyl)-4-morpholinopyrimidine-5-carboxamide
PubChem: 142592633
ChEMBL: CHEMBL4295242
LyCHI: SYNJHHB7XXW9
Target Activities
PDE4A
cAMP-specific 3',5'-cyclic phosphodiesterase 4A
2 Activities
PDE4B
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
2 Activities
PDE3B
cGMP-inhibited 3',5'-cyclic phosphodiesterase B
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.02 | Eur J Med Chem, (2018) 145:None:673 | ||||
PDE4D
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.42 | Eur J Med Chem, (2018) 145:None:673 | ||||
PDE4C
cAMP-specific 3',5'-cyclic phosphodiesterase 4C
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.81 | Eur J Med Chem, (2018) 145:None:673 | ||||