CHEMBL306090
Ligand Summary
Name: N*4*-(2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-2-hydroxymethyl-3-p-tolyl-succinamide
PubChem: 9907830
ChEMBL: CHEMBL306090
LyCHI: RN46JUGAQGGQ
Target Activities
ADAM17
Disintegrin and metalloproteinase domain-containing protein 17
2 Activities
TNF
Tumor necrosis factor
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.57 | J. Med. Chem., (2002) 45:11:2289 | ||||
MMP3
Stromelysin-1
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 7.82 | J. Med. Chem., (2002) 45:11:2289 | ||||
MMP2
72 kDa type IV collagenase
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 9.52 | J. Med. Chem., (2002) 45:11:2289 | ||||
MMP1
Interstitial collagenase
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 8.7 | J. Med. Chem., (2002) 45:11:2289 | ||||