CHEMBL4217988
Ligand Summary
Name: 3-cyano-4-(3-(2-((2-(piperidin-4-yl)ethylamino)methyl)pyridin-4-yl)-3'-(trifluoromethyl)biphenyl-4-yloxy)-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
PubChem: 118540795
ChEMBL: CHEMBL4217988
LyCHI: RGWKXKPUR18N
Target Activities
SCN1A
Sodium channel protein type 1 subunit alpha
2 Activities
SCN5A
Sodium channel protein type 5 subunit alpha
2 Activities
SCN4A
Sodium channel protein type 4 subunit alpha
2 Activities
SCN2A
Sodium channel protein type 2 subunit alpha
2 Activities
SCN9A
Sodium channel protein type 9 subunit alpha
2 Activities
SCN8A
Sodium channel protein type 8 subunit alpha
2 Activities
SCN3A
Sodium channel protein type 3 subunit alpha
2 Activities
SLC5A7
High affinity choline transporter 1
2 Activities
KCNH2
Potassium voltage-gated channel subfamily H member 2
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 5.96 | Bioorg Med Chem Lett, (2017) 27:21:4805 | ||||
SCN7A
Sodium channel protein type 7 subunit alpha
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 11 | J Med Chem, (2019) 62:19:8695 | ||||