CHEMBL458997
Ligand Summary
Name: NVP-TAE 226
PubChem: 9934347
Guide to Pharmacology: 9382
ChEMBL: CHEMBL458997
LyCHI: R5Q9CBFZGX71
Target Activities
PTK2
Focal adhesion kinase 1
4 Activities
Items per page:
1 – 4 of 4
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.15 | Bioorg. Med. Chem. Lett., (2013) 23:16:4552 | ||||
IC50 | 8.15 | J. Med. Chem., (2015) 58:1:237 | ||||
IC50 | 8.26 | Med Chem Res, (2013) None:None:1 | ||||
IC50 | 8.26000023 | |||||
ALK
ALK tyrosine kinase receptor
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.3 | Bioorg. Med. Chem. Lett., (2011) 21:1:463 | ||||
MAPK10
Mitogen-activated protein kinase 10
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.92 | MedChemComm, (2012) 3:2:238 | ||||
AURKA
Aurora kinase A
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.4 | Eur J Med Chem, (2016) 124:None:896 | ||||
INSR
Insulin receptor
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.6 | Bioorg. Med. Chem. Lett., (2011) 21:1:463 | ||||
IGF1R
Insulin-like growth factor 1 receptor
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.8499999 | |||||