Pharos : Ligand Details - R529WVVT6JA6

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Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

Name: Posaconazole

PubChem: 468595

ChEMBL: CHEMBL1397

LyCHI: R529WVVT6JA6

Target Activities

Explore Associated and Predicted Targets

CYP3A4

Tclin

Cytochrome P450 3A4

6 Activities

Items per page:

1 – 6 of 6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	7.3		Bioorg. Med. Chem. Lett., (2014) 24:15:3455	24948565

IC50	7.12		Bioorg Med Chem Lett, (2017) 27:15:3243	28651982

IC50	7.09		J. Med. Chem., (2010) 53:10:3887	20429511

IC50	6.82		Eur J Med Chem, (2019) 163:None:320	30529635

IC50	6.46		J. Med. Chem., (2009) 52:6:1639	19239254

IC50	6.17		Eur J Med Chem, (2019) 179:None:779	31288127

CYP17A1

Tclin

Steroid 17-alpha-hydroxylase/17,20 lyase

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	7.38		Bioorg Med Chem Lett, (2017) 27:15:3243	28651982

CYP11B1

Tclin

Cytochrome P450 11B1, mitochondrial

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.51		Bioorg Med Chem Lett, (2017) 27:15:3243	28651982

CYP11B2

Tchem

Cytochrome P450 11B2, mitochondrial

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	7.68		Bioorg Med Chem Lett, (2017) 27:15:3243	28651982