pinometostat
Ligand Summary
Name: pinometostat
PubChem: 57345410
Guide to Pharmacology: 7019
ChEMBL: CHEMBL3414626
LyCHI: QJLJRL1W4FPJ
Target Activities
DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific
10 Activities
Items per page:
1 – 10 of 10
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 10.1 | |||||
Ki | 10.92 | ACS Med Chem Lett, (2017) 8:3:338 | ||||
Ki | 10.1 | J. Med. Chem., (2015) 58:4:1596 | ||||
Ki | 10.1 | J Med Chem, (2019) 62:22:10005 | ||||
IC50 | 9.13 | None, (2016) None:None:None | ||||
IC50 | 8.52 | J. Med. Chem., (2015) 58:4:1596 | ||||
IC50 | 8.46 | J. Med. Chem., (2015) 58:4:1596 | ||||
IC50 | 8.15 | ACS Med Chem Lett, (2017) 8:3:338 | ||||
IC50 | 8.11 | Bioorg Med Chem Lett, (2017) 27:22:4960 | ||||
IC50 | 7.28 | ACS Med Chem Lett, (2017) 8:3:338 | ||||