Pharos : Ligand Details - QJ7SXJ6U6BLW

You are using an outdated browser. Please upgrade your browser to improve your experience.

Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

Name: (S)-dimetindene

PubChem: 6604866

Guide to Pharmacology: 10104

ChEMBL: CHEMBL1493369

LyCHI: QJ7SXJ6U6BLW

Target Activities

Explore Associated and Predicted Targets

HRH1

Tclin

Histamine H1 receptor

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	7.16			12593665

Ki	7.16		J. Med. Chem., (2003) 46:5:856	12593665

CHRM2

Tclin

Muscarinic acetylcholine receptor M2

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	7.52			12593665

Ki	7.52		J. Med. Chem., (2003) 46:5:856	12593665

CHRM1

Tclin

Muscarinic acetylcholine receptor M1

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	6.72			12593665

CHRM3

Tclin

Muscarinic acetylcholine receptor M3

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	6.86			12593665

CHRM4

Tclin

Muscarinic acetylcholine receptor M4

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	6.53			12593665

CHRM5

Tclin

Muscarinic acetylcholine receptor M5

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	6.12			12593665

CYP2C9

Tchem

Cytochrome P450 2C9

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
AC50	6.3		None, None:None:None