Pharos : Ligand Details - QGASR1C53UZ5

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Ligand Summary

Ligand Structure

chemical structure image

Synonyms & Links

Name: 3-(1H-Indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5-dione

PubChem: 10296883

Guide to Pharmacology: 7946

ChEMBL: CHEMBL565612

LyCHI: QGASR1C53UZ5

Target Activities

Items per page:

10

1 – 6 of 6

PRKCD

Tclin

Protein kinase C delta type

3 Activities

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1 – 3 of 3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	8.89		J. Med. Chem., (2009) 52:20:6193	19827831

IC50	8.89		J. Med. Chem., (2011) 54:17:6028	21797275

IC50	8.89000034			19827831

PRKCQ

Tchem

Protein kinase C theta type

3 Activities

Items per page:

1 – 3 of 3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	9		J. Med. Chem., (2009) 52:20:6193	19827831

IC50	9		J. Med. Chem., (2011) 54:17:6028	21797275

IC50	9			19827831

PRKCE

Tchem

Protein kinase C epsilon type

3 Activities

Items per page:

1 – 3 of 3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	8.21		J. Med. Chem., (2009) 52:20:6193	19827831

IC50	8.21		J. Med. Chem., (2011) 54:17:6028	21797275

IC50	8.21000004			19827831

PRKCH

Tchem

Protein kinase C eta type

3 Activities

Items per page:

1 – 3 of 3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	8.21		J. Med. Chem., (2009) 52:20:6193	19827831

IC50	8.21		J. Med. Chem., (2011) 54:17:6028	21797275

IC50	8.21000004			19827831

PRKCA

Tchem

Protein kinase C alpha type

3 Activities

Items per page:

1 – 3 of 3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	8.68		J. Med. Chem., (2009) 52:20:6193	19827831

IC50	8.68		J. Med. Chem., (2011) 54:17:6028	21797275

IC50	8.68000031			19827831

PRKCB

Tchem

Protein kinase C beta type

3 Activities

Items per page:

1 – 3 of 3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	8.7		J. Med. Chem., (2009) 52:20:6193	19827831

IC50	8.7		J. Med. Chem., (2011) 54:17:6028	21797275

IC50	8.69999981			19827831