CHEMBL3900593
Ligand Summary
Name: (+/-)-3-[[4-Ethoxy-3-(1-methyl-7-oxo-3-propyl-6H-pyrazolo[4,3-d]-pyrimidin-5-yl)phenyl]methyl]cyclobutanecarbohydroxamic Acid
PubChem: 137290273
ChEMBL: CHEMBL3900593
LyCHI: Q6VKV8VL23A4
Target Activities
HDAC1
Histone deacetylase 1
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.51 | J Med Chem, (2016) 59:19:8967 | ||||
PDE5A
cGMP-specific 3',5'-cyclic phosphodiesterase
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.22 | J Med Chem, (2016) 59:19:8967 | ||||
HDAC6
Histone deacetylase 6
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.04 | J Med Chem, (2016) 59:19:8967 | ||||
PDE6C
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.59 | J Med Chem, (2016) 59:19:8967 | ||||
HDAC2
Histone deacetylase 2
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.31 | J Med Chem, (2016) 59:19:8967 | ||||