CHEMBL256147,CHEMBL3217190
Ligand Summary
NCATS Inxight: Drugs: 46906075,90665205
Name: 2-Amino-5-(N'-methyl-guanidino)-pentanoic acid
PubChem: 46906075,90665205
ChEMBL: CHEMBL256147,CHEMBL3217190
LyCHI: NYZF2KPYRCWP
Target Activities
Items per page:
10
1 – 3 of 3
NOS3
Nitric oxide synthase, endothelial
6 Activities
Items per page:
1 – 6 of 6
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.19 | ACS Med. Chem. Lett., (2012) 3:3:227 | ||||
IC50 | 6.19 | J. Med. Chem., (2012) 55:6:2882 | ||||
IC50 | 6.19 | J. Med. Chem., (2011) 54:20:7408 | ||||
IC50 | 6.27 | Bioorg. Med. Chem. Lett., (2003) 13:12:1981 | ||||
Ki | 6.4 | Bioorg. Med. Chem. Lett., (1997) 7:13:1763 | ||||
Ki | 6.4 | J. Med. Chem., (1998) 41:15:2858 | ||||
NOS1
Nitric oxide synthase, brain
6 Activities
Items per page:
1 – 6 of 6
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.02 | ACS Med. Chem. Lett., (2012) 3:3:227 | ||||
IC50 | 6.02 | J. Med. Chem., (2012) 55:6:2882 | ||||
IC50 | 6.02 | J. Med. Chem., (2011) 54:20:7408 | ||||
IC50 | 6.05 | Bioorg. Med. Chem. Lett., (2003) 13:12:1981 | ||||
Ki | 6.08 | Bioorg. Med. Chem. Lett., (1997) 7:13:1763 | ||||
Ki | 6.08 | J. Med. Chem., (1998) 41:15:2858 | ||||
NOS2
Nitric oxide synthase, inducible
4 Activities
Items per page:
1 – 4 of 4
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6 | Bioorg. Med. Chem. Lett., (2003) 13:12:1981 | ||||
Ki | 6.07 | Bioorg. Med. Chem. Lett., (1997) 7:13:1763 | ||||
Ki | 6.07 | J. Med. Chem., (1998) 41:15:2858 | ||||
IC50 | 8.75 | ACS Med. Chem. Lett., (2012) 3:3:227 | ||||