oxotremorine
Ligand Summary
Name: oxotremorine
PubChem: 4630
Guide to Pharmacology: 302
ChEMBL: CHEMBL7634
LyCHI: NUX1N7J2S33B
Target Activities
CHRM1
Muscarinic acetylcholine receptor M1
6 Activities
Items per page:
1 – 6 of 6
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
6 | ||||||
5.5 | ||||||
Ki | 8.95 | Bioorg. Med. Chem., (2008) 16:6:3049 | ||||
EC50 | 8.8 | Bioorg. Med. Chem. Lett., (2015) 25:7:1546 | ||||
IC50 | 8.64 | Bioorg. Med. Chem. Lett., (2001) 11:21:2855 | ||||
Ki | 7.77 | J. Med. Chem., (2000) 43:13:2514 | ||||
CHRM4
Muscarinic acetylcholine receptor M4
5 Activities
Items per page:
1 – 5 of 5
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
5.2 | ||||||
Ki | 8.82 | J. Med. Chem., (2000) 43:13:2514 | ||||
EC50 | 8.05 | ACS Med Chem Lett, (2019) 10:6:941 | ||||
EC50 | 7.85 | ACS Med Chem Lett, (2019) 10:6:941 | ||||
EC50 | 7.48 | J. Med. Chem., (1995) 38:12:2188 | ||||
CHRM2
Muscarinic acetylcholine receptor M2
3 Activities
CHRM3
Muscarinic acetylcholine receptor M3
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
5.3 | ||||||
CHRM5
Muscarinic acetylcholine receptor M5
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
EC50 | 7.26 | J. Med. Chem., (1995) 38:12:2188 | ||||
CYP2C19
Cytochrome P450 2C19
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
AC50 | 6.8 | None, None:None:None | ||||