Pharos : Ligand Details

Target Activities

Explore Associated and Predicted Targets

PIK3CG

Tclin

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

2 Activities

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1 – 2 of 2

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
IC50	7.08		17685602

Kd	8.28	Nat. Biotechnol., (2011) 29:11:1046	22037378

PIK3CA

Tclin

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	5.89			17685602

PIK3CB

Tchem

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

1 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	5.92			17685602

PIK3CD

Tclin

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform

1 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.63			17685602

DCK

Tchem

Deoxycytidine kinase

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	7.92		Science, (2017) 358:6367:None	29191878

PIK3C2B

Tchem

Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta

1 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	8.14		Nat. Biotechnol., (2011) 29:11:1046	22037378

TRPM6

Tchem

Transient receptor potential cation channel subfamily M member 6

1 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	8.1		Nat. Biotechnol., (2011) 29:11:1046	22037378

PIK3C2G

Tchem

Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	8.49		Nat. Biotechnol., (2011) 29:11:1046	22037378