CHEMBL2338351
Ligand Summary
Name: 2-methyl-N-((1-(4-phenylpiperazin-1-yl)cyclohexyl)methyl)-1,2,3,4-tetrahydroisoquinoline-5-carboxamide
PubChem: 71625847
ChEMBL: CHEMBL2338351
LyCHI: NMQYDVBWNM9V
Target Activities
P2RX7
P2X purinoceptor 7
4 Activities
Items per page:
1 – 4 of 4
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 7.9 | ACS Med. Chem. Lett., (2013) 4:4:419 | ||||
IC50 | 7.7 | ACS Med. Chem. Lett., (2013) 4:4:419 | ||||
IC50 | 7.4 | ACS Med. Chem. Lett., (2013) 4:4:419 | ||||
IC50 | 6.7 | ACS Med. Chem. Lett., (2013) 4:4:419 | ||||
SLC6A4
Sodium-dependent serotonin transporter
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 7.8 | ACS Med. Chem. Lett., (2013) 4:4:419 | ||||
SLC6A3
Sodium-dependent dopamine transporter
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.54 | ACS Med. Chem. Lett., (2013) 4:4:419 | ||||