A-366
Ligand Summary
Name: A-366
PubChem: 76285486
Guide to Pharmacology: 8238
ChEMBL: CHEMBL3109630
LyCHI: NM25ZJ29PWYC
Target Activities
EHMT2
Histone-lysine N-methyltransferase EHMT2
7 Activities
Items per page:
1 – 7 of 7
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.48 | |||||
IC50 | 8.52 | ACS Med. Chem. Lett., (2014) 5:2:205 | ||||
IC50 | 8.52 | J Med Chem, (2019) 62:20:8996 | ||||
IC50 | 8.48 | ACS Med. Chem. Lett., (2014) 5:2:205 | ||||
IC50 | 8.48 | J. Med. Chem., (2015) 58:6:2569 | ||||
IC50 | 8.48 | Bioorg Med Chem, (2016) 24:22:6102 | ||||
IC50 | 7.89 | Bioorg Med Chem Lett, (2019) 29:17:2516 | ||||
SPIN1
Spindlin-1
6 Activities
Items per page:
1 – 6 of 6
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.14 | J Med Chem, (2019) 62:20:8996 | ||||
Kd | 6.96 | J Med Chem, (2019) 62:20:8996 | ||||
Kd | 6.75 | J Med Chem, (2019) 62:20:9008 | ||||
IC50 | 6.73 | J Med Chem, (2019) 62:20:9008 | ||||
IC50 | 6.68 | J Med Chem, (2019) 62:20:8996 | ||||
Kd | 6.41 | J Med Chem, (2019) 62:20:9008 | ||||