Pharos : Ligand Details - MZGN41PZ1HQ7

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Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

Name: AT-406

PubChem: 25022340

Guide to Pharmacology: 7729

ChEMBL: CHEMBL2158051

LyCHI: MZGN41PZ1HQ7

Target Activities

Explore Associated and Predicted Targets

XIAP

Tchem

E3 ubiquitin-protein ligase XIAP

6 Activities

Items per page:

1 – 6 of 6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	7.18			21443232

EC50	7.47		J. Med. Chem., (2015) 58:16:6574	26218264

IC50	7.38		J Med Chem, (2019) 62:20:9188	31550155

IC50	7.32		J Med Chem, (2019) 62:20:9188	31550155

Ki	7.18		J. Med. Chem., (2011) 54:8:2714	21443232

IC50	6.65		J. Med. Chem., (2011) 54:8:2714	21443232

BIRC2

Tchem

Baculoviral IAP repeat-containing protein 2

5 Activities

Items per page:

1 – 5 of 5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	8.72			21443232

Ki	8.72		J. Med. Chem., (2011) 54:8:2714	21443232

IC50	7.91		J. Med. Chem., (2011) 54:8:2714	21443232

IC50	7.47		J Med Chem, (2019) 62:20:9188	31550155

IC50	7.46		J Med Chem, (2019) 62:20:9188	31550155

BIRC3

Tchem

Baculoviral IAP repeat-containing protein 3

5 Activities

Items per page:

1 – 5 of 5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	8.29			21443232

Ki	8.29		J. Med. Chem., (2011) 54:8:2714	21443232

IC50	7.66		J. Med. Chem., (2011) 54:8:2714	21443232

IC50	7.36		J Med Chem, (2019) 62:20:9188	31550155

IC50	6.88		J Med Chem, (2019) 62:20:9188	31550155