Pharos : Ligand Details - MLJBWZZWNBJ9

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Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

Name: L-796449

PubChem: 9891946

Guide to Pharmacology: 2689

ChEMBL: CHEMBL278994

LyCHI: MLJBWZZWNBJ9

Target Activities

Explore Associated and Predicted Targets

PPARD

Tchem

Peroxisome proliferator-activated receptor delta

6 Activities

Items per page:

1 – 6 of 6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
	8.7			15293980 10037770

EC50	8.22		Bioorg. Med. Chem. Lett., (2003) 13:7:1277	12657263

IC50	8.22		Bioorg. Med. Chem. Lett., (2003) 13:7:1277	12657263

IC50	8.22		Bioorg. Med. Chem., (2012) 20:11:3523	22564380

EC50	8.1		J. Med. Chem., (2000) 43:4:527	10691680

EC50	8.1		Eur. J. Med. Chem., (2012) 53:None:190	22534184

PPARG

Tclin

Peroxisome proliferator-activated receptor gamma

6 Activities

Items per page:

1 – 6 of 6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
	8.7			10037770

EC50	8.28		J. Med. Chem., (2000) 43:4:527	10691680

EC50	8.05		Bioorg. Med. Chem. Lett., (2003) 13:7:1277	12657263

IC50	7.03		Bioorg. Med. Chem. Lett., (2003) 13:7:1277	12657263

IC50	7.03		Eur. J. Med. Chem., (2011) 46:6:2513	21482446

IC50	7.03		Bioorg. Med. Chem., (2012) 20:11:3523	22564380

PPARA

Tclin

Peroxisome proliferator-activated receptor alpha

4 Activities

Items per page:

1 – 4 of 4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
EC50	8.39		J. Med. Chem., (2000) 43:4:527	10691680

EC50	7.75		Bioorg. Med. Chem. Lett., (2003) 13:7:1277	12657263

IC50	7.27		Bioorg. Med. Chem. Lett., (2003) 13:7:1277	12657263

IC50	7.27		Bioorg. Med. Chem., (2012) 20:11:3523	22564380