Pharos : Ligand Details - MBRKC1KZKW64

You are using an outdated browser. Please upgrade your browser to improve your experience.

Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

Name: (3aR,5R,6S,7R,7aR)-5-(hydroxymethyl)-2-methyl-5,6,7,7a-tetrahydropyrano[3,2-d]thiazole-6,7-diol

PubChem: 5289024

ChEMBL: CHEMBL257158

LyCHI: MBRKC1KZKW64

Target Activities

Explore Associated and Predicted Targets

OGA

Tchem

Protein O-GlcNAcase

3 Activities

Items per page:

1 – 3 of 3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	8		Bioorg. Med. Chem., (2010) 18:19:7058	20822912

Ki	7.16		Bioorg. Med. Chem. Lett., (2008) 18:9:2944	18406613

Ki	6.75		ACS Med Chem Lett, (2018) 9:12:1241	30613333

HEXB

Tchem

Beta-hexosaminidase subunit beta

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	6.72		ACS Med Chem Lett, (2018) 9:12:1241	30613333

Ki	6.54		ACS Med. Chem. Lett., (2013) 4:6:527	24900704

HEXA

Tchem

Beta-hexosaminidase subunit alpha

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	6.57		ACS Med. Chem. Lett., (2013) 4:6:527	24900704