Pharos : Ligand Details - M35FNYX8R29V

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Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

Name: 7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)-3-(pyrazin-2-ylmethylamino)pyrido[3,4-b]pyrazin-2(1H)-one

PubChem: 45486504

Guide to Pharmacology: 8811

ChEMBL: CHEMBL565305

LyCHI: M35FNYX8R29V

Target Activities

PDE5A

Tclin

cGMP-specific 3',5'-cyclic phosphodiesterase

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	10.3			19631533

IC50	10.22		Bioorg. Med. Chem. Lett., (2009) 19:17:5209	19631533

PDE6A

Tclin

Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	8.01			19631533

IC50	8.33		Bioorg. Med. Chem. Lett., (2009) 19:17:5209	19631533