CHEMBL3321792
Ligand Summary
Name: 3-(4-chlorophenyl)-8-(3-(2-fluorophenylthio)propyl)-8-azabicyclo[3.2.1]octan-3-ol
PubChem: 118709751
ChEMBL: CHEMBL3321792
LyCHI: LCR2YT5DQUDX
Target Activities
SIGMAR1
Sigma non-opioid intracellular receptor 1
2 Activities
TMEM97
Sigma intracellular receptor 2
2 Activities
DRD2
D(2) dopamine receptor
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 8.32 | Bioorg. Med. Chem. Lett., (2014) 24:17:4294 | ||||
DRD3
D(3) dopamine receptor
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 8.89 | Bioorg. Med. Chem. Lett., (2014) 24:17:4294 | ||||
SLC6A4
Sodium-dependent serotonin transporter
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 6.99 | Bioorg. Med. Chem. Lett., (2014) 24:17:4294 | ||||
HTR1A
5-hydroxytryptamine receptor 1A
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 8.09 | Bioorg. Med. Chem. Lett., (2014) 24:17:4294 | ||||
SLC6A3
Sodium-dependent dopamine transporter
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 6.45 | Bioorg. Med. Chem. Lett., (2014) 24:17:4294 | ||||
SLC6A2
Sodium-dependent noradrenaline transporter
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 6.33 | Bioorg. Med. Chem. Lett., (2014) 24:17:4294 | ||||