CHEMBL4517404
Ligand Summary
Name: (S)-1-((S)-2-hydroxy-2-phenylethyl)-8-morpholino-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one
PubChem: 49853889
ChEMBL: CHEMBL4517404
LyCHI: LAJ9PHUVLV6D
Target Activities
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.22 | J Med Chem, (2018) 61:11:4656 | ||||
PIK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.7 | J Med Chem, (2018) 61:11:4656 | ||||