Pharos : Ligand Details - JV75JK9DM58T

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Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

Name: 3-(3,5-dichloro-4-(4-hydroxy-3-isopropylphenoxy)phenyl)propanoic acid

PubChem: 10904700

ChEMBL: CHEMBL418432

LyCHI: JV75JK9DM58T

Target Activities

Explore Associated and Predicted Targets

THRB

Tclin

Thyroid hormone receptor beta

4 Activities

Items per page:

1 – 4 of 4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	9.82		J. Med. Chem., (2003) 46:9:1580	12699376

IC50	9.82		Bioorg. Med. Chem., (2007) 15:15:5251	17524652

IC50	9.82		Bioorg. Med. Chem., (2007) 15:13:4609	17467994

EC50	9.55		J. Med. Chem., (2003) 46:9:1580	12699376

THRA

Tclin

Thyroid hormone receptor alpha

3 Activities

Items per page:

1 – 3 of 3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
EC50	9.52		J. Med. Chem., (2003) 46:9:1580	12699376

IC50	9.12		J. Med. Chem., (2003) 46:9:1580	12699376

IC50	9.12		Bioorg. Med. Chem., (2007) 15:13:4609	17467994