talmapimod
Ligand Summary
Name: talmapimod
PubChem: 9871074
Guide to Pharmacology: 7817
ChEMBL: CHEMBL514201
LyCHI: JPKVUCUGMAKB
Target Activities
MAPK14
Mitogen-activated protein kinase 14
6 Activities
Items per page:
1 – 6 of 6
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
---|---|---|---|---|---|---|
IC50 | 8.05 | |||||
Kd | 9.32 | J. Med. Chem., (2010) 53:6:2345 | ||||
Kd | 8.1 | Science, (2017) 358:6367:None | ||||
IC50 | 8.05 | Bioorg. Med. Chem. Lett., (2010) 20:3:828 | ||||
IC50 | 8.05 | J. Med. Chem., (2010) 53:6:2345 | ||||
IC50 | 8 | J Med Chem, (2018) 61:15:6421 | ||||
MAPK11
Mitogen-activated protein kinase 11
2 Activities
MAPKAPK2
MAP kinase-activated protein kinase 2
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
---|---|---|---|---|---|---|
Kd | 7.72 | Science, (2017) 358:6367:None | ||||
ACTR2
Actin-related protein 2
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
---|---|---|---|---|---|---|
Kd | 8.4 | Science, (2017) 358:6367:None | ||||