Pharos : Ligand Details - JPKVUCUGMAKB

You are using an outdated browser. Please upgrade your browser to improve your experience.

Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

Name: talmapimod

PubChem: 9871074

Guide to Pharmacology: 7817

ChEMBL: CHEMBL514201

LyCHI: JPKVUCUGMAKB

Target Activities

Explore Associated and Predicted Targets

MAPK14

Tchem

Mitogen-activated protein kinase 14

6 Activities

Items per page:

1 – 6 of 6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	8.05			20071169

Kd	9.32		J. Med. Chem., (2010) 53:6:2345	19950901

Kd	8.1		Science, (2017) 358:6367:None	29191878

IC50	8.05		Bioorg. Med. Chem. Lett., (2010) 20:3:828	20071169

IC50	8.05		J. Med. Chem., (2010) 53:6:2345	19950901

IC50	8		J Med Chem, (2018) 61:15:6421	29620890

MAPK11

Tchem

Mitogen-activated protein kinase 11

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	7.01			20071169

Kd	7.82		J. Med. Chem., (2010) 53:6:2345	19950901

MAPKAPK2

Tchem

MAP kinase-activated protein kinase 2

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	7.72		Science, (2017) 358:6367:None	29191878

ACTR2

Tchem

Actin-related protein 2

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	8.4		Science, (2017) 358:6367:None	29191878