CHEMBL4451634
Ligand Summary
Name: 2-(4-(2-((2-(3-((2-Amino-5-(cyclopropylmethoxy)-3,3-dimethyl-3H-indol-6-yl)oxy)propyl)isoindolin-5-yl)oxy)ethyl)-1H-1,2,3-triazol-1-yl)-1-(4-(2-(pyrrolidin-1-yl)ethyl)piperidin-1-yl)ethan-1-one
PubChem: 137349494
ChEMBL: CHEMBL4451634
LyCHI: JHZYWCF7LRGY
Target Activities
SPIN1
Spindlin-1
5 Activities
Items per page:
1 – 5 of 5
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 8 | J Med Chem, (2019) 62:20:9008 | ||||
IC50 | 7.48 | J Med Chem, (2019) 62:20:9008 | ||||
Kd | 7.26 | J Med Chem, (2019) 62:20:9008 | ||||
Kd | 6.95 | J Med Chem, (2019) 62:20:9008 | ||||
EC50 | 6.57 | J Med Chem, (2019) 62:20:9008 | ||||
SPIN4
Spindlin-4
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 7.74 | J Med Chem, (2019) 62:20:9008 | ||||
SPIN3
Spindlin-3
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 6.88 | J Med Chem, (2019) 62:20:9008 | ||||
SPIN2B
Spindlin-2B
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 7.34 | J Med Chem, (2019) 62:20:9008 | ||||