Pharos : Ligand Details - JHD7SC6KYURG

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Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

Name: BAY-299

PubChem: 122705990

Guide to Pharmacology: 9524

ChEMBL: CHEMBL4086276

LyCHI: JHD7SC6KYURG

Target Activities

Explore Associated and Predicted Targets

BRD1

Tchem

Bromodomain-containing protein 1

13 Activities

Items per page:

1 – 10 of 13

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	8.22

IC50	8.22		J Med Chem, (2017) 60:1:157	27935314

Kd	7.44		J Med Chem, (2017) 60:9:4002	28402630

Kd	7.43		J Med Chem, (2017) 60:9:4002	28402630

Kd	7.35		J Med Chem, (2017) 60:9:4002	28402630

IC50	7.21		J Med Chem, (2017) 60:9:4002	28402630

IC50	7.17		J Med Chem, (2017) 60:9:4002	28402630

IC50	7.13		J Med Chem, (2017) 60:9:4002	28402630

IC50	7.01		J Med Chem, (2017) 60:9:4002	28402630

IC50	6.45		J Med Chem, (2017) 60:9:4002	28402630

TAF1

Tchem

Transcription initiation factor TFIID subunit 1

6 Activities

Items per page:

1 – 6 of 6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	7.89

IC50	8.1		J Med Chem, (2017) 60:9:4002	28402630

IC50	7.96		J Med Chem, (2017) 60:9:4002	28402630

IC50	7.89		J Med Chem, (2017) 60:1:157	27935314

Kd	7.78		J Med Chem, (2017) 60:9:4002	28402630

IC50	7.77		J Med Chem, (2017) 60:9:4002	28402630

TAF1L

Tchem

Transcription initiation factor TFIID subunit 1-like

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.97		J Med Chem, (2017) 60:9:4002	28402630

Kd	6.63		J Med Chem, (2017) 60:9:4002	28402630