CHEMBL252387
Ligand Summary
Name: 3-(2,5-dimethoxyphenyl)-6-(3,4-dimethoxyphenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
PubChem: 17757146
ChEMBL: CHEMBL252387
LyCHI: J8Y2K4BWM4Q4
Target Activities
PDE4B
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
2 Activities
PDE4A
cAMP-specific 3',5'-cyclic phosphodiesterase 4A
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.17 | Bioorg. Med. Chem. Lett., (2009) 19:13:3686 | ||||
PDE3B
cGMP-inhibited 3',5'-cyclic phosphodiesterase B
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.14 | Bioorg. Med. Chem. Lett., (2009) 19:13:3686 | ||||
PDE4D
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.31 | Bioorg. Med. Chem. Lett., (2009) 19:13:3686 | ||||
PDE10A
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.08 | Bioorg. Med. Chem. Lett., (2009) 19:13:3686 | ||||
PDE4C
cAMP-specific 3',5'-cyclic phosphodiesterase 4C
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.34 | Bioorg. Med. Chem. Lett., (2009) 19:13:3686 | ||||