Pharos : Ligand Details - HX998FFQD3UR

You are using an outdated browser. Please upgrade your browser to improve your experience.

Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

Name: US8877795, 12

PubChem: 1361334

ChEMBL: CHEMBL183906

LyCHI: HX998FFQD3UR

Target Activities

Explore Associated and Predicted Targets

PIM1

Tchem

Serine/threonine-protein kinase pim-1

5 Activities

Items per page:

1 – 5 of 5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	7.77		J Med Chem, (2017) 60:7:2853	28291344

IC50	7.62		Bioorg. Med. Chem. Lett., (2009) 19:11:3019	19414255

IC50	7.62		J. Med. Chem., (2009) 52:1:74	19072652

IC50	7.62		J. Med. Chem., (2012) 55:6:2641	22339127

Ki	7.62		J. Med. Chem., (2012) 55:19:8199	22924342

TTR

Tclin

Transthyretin

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.09		None, (2014) None:None:None

CISD1

Tchem

CDGSH iron-sulfur domain-containing protein 1

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	6.53		Bioorg Med Chem Lett, (2016) 26:21:5350	27687671