Pharos : Ligand Details

Target Activities

Items per page:

1 – 10 of 45

ABL1

Tclin

Tyrosine-protein kinase ABL1

17 Activities

Items per page:

1 – 10 of 17

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
Kd	7.6	Nat. Biotechnol., (2011) 29:11:1046	22037378

Kd	7.64	Nat. Biotechnol., (2008) 26:1:127	18183025

Kd	7.89	Nat. Biotechnol., (2011) 29:11:1046	22037378

Kd	7.89	Nat. Biotechnol., (2011) 29:11:1046	22037378

Kd	7.89	Nat. Biotechnol., (2011) 29:11:1046	22037378

Kd	8	Nat. Biotechnol., (2011) 29:11:1046	22037378

Kd	8.08	Nat. Biotechnol., (2008) 26:1:127	18183025

Kd	8.21	Nat. Biotechnol., (2008) 26:1:127	18183025

Kd	8.25	Nat. Biotechnol., (2008) 26:1:127	18183025

Kd	8.3	Nat. Biotechnol., (2008) 26:1:127	18183025

FLT3

Tclin

Receptor-type tyrosine-protein kinase FLT3

16 Activities

Items per page:

1 – 10 of 16

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
Kd	7.96	Nat. Biotechnol., (2008) 26:1:127	18183025

Kd	7.96	Nat. Biotechnol., (2008) 26:1:127	18183025

Kd	7.96	Nat. Biotechnol., (2011) 29:11:1046	22037378

Kd	7.96	Nat. Biotechnol., (2011) 29:11:1046	22037378

IC50	8.3	J. Med. Chem., (2013) 56:17:6991	23937569

Kd	8.31	Nat. Biotechnol., (2008) 26:1:127	18183025

Kd	8.31	Nat. Biotechnol., (2011) 29:11:1046	22037378

Kd	8.64	Nat. Biotechnol., (2008) 26:1:127	18183025

Kd	8.64	Nat. Biotechnol., (2011) 29:11:1046	22037378

Kd	9.1	Nat. Biotechnol., (2008) 26:1:127	18183025

KIT

Tclin

Mast/stem cell growth factor receptor Kit

10 Activities

Items per page:

1 – 10 of 10

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
Kd	7.75	Nat. Biotechnol., (2008) 26:1:127	18183025

Kd	7.75	Nat. Biotechnol., (2011) 29:11:1046	22037378

Kd	8.27	Eur. J. Med. Chem., (2011) 46:6:2043	21429632

Kd	8.27	Nat. Biotechnol., (2008) 26:1:127	18183025

Kd	8.27	Nat. Biotechnol., (2011) 29:11:1046	22037378

Kd	8.3	Nat. Biotechnol., (2008) 26:1:127	18183025

Kd	8.3	Nat. Biotechnol., (2011) 29:11:1046	22037378

Kd	8.36	Nat. Biotechnol., (2011) 29:11:1046	22037378

Kd	8.68	Nat. Biotechnol., (2011) 29:11:1046	22037378

IC50	6.30000019		17638907

RET

Tclin

Proto-oncogene tyrosine-protein kinase receptor Ret

7 Activities

Items per page:

1 – 7 of 7

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
Kd	7.77	Nat. Biotechnol., (2008) 26:1:127	18183025

Kd	7.77	Nat. Biotechnol., (2011) 29:11:1046	22037378

Kd	8.35	Nat. Biotechnol., (2008) 26:1:127	18183025

Kd	8.35	Nat. Biotechnol., (2011) 29:11:1046	22037378

Kd	8.37	Nat. Biotechnol., (2011) 29:11:1046	22037378

Kd	8.49	Nat. Biotechnol., (2011) 29:11:1046	22037378

IC50	6.05999994		17638907

MKNK2

Tchem

MAP kinase-interacting serine/threonine-protein kinase 2

3 Activities

Items per page:

1 – 3 of 3

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
IC50	7.7	J. Med. Chem., (2016) 59:7:3063	27011159

Kd	8.52	Nat. Biotechnol., (2008) 26:1:127	18183025

Kd	8.52	Nat. Biotechnol., (2011) 29:11:1046	22037378

CDK17

Tchem

Cyclin-dependent kinase 17

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
Kd	7.82	Nat. Biotechnol., (2008) 26:1:127	18183025

Kd	7.82	Nat. Biotechnol., (2011) 29:11:1046	22037378

CDK19

Tchem

Cyclin-dependent kinase 19

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
Kd	8.82	Nat. Biotechnol., (2008) 26:1:127	18183025

Kd	8.82	Nat. Biotechnol., (2011) 29:11:1046	22037378

CSF1R

Tclin

Macrophage colony-stimulating factor 1 receptor

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
Kd	8.24	Nat. Biotechnol., (2008) 26:1:127	18183025

Kd	8.24	Nat. Biotechnol., (2011) 29:11:1046	22037378

DDR1

Tchem

Epithelial discoidin domain-containing receptor 1

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
Kd	9.16	Nat. Biotechnol., (2008) 26:1:127	18183025

Kd	9.16	Nat. Biotechnol., (2011) 29:11:1046	22037378

STK10

Tchem

Serine/threonine-protein kinase 10

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
Kd	9.04	Nat. Biotechnol., (2008) 26:1:127	18183025

Kd	9.04	Nat. Biotechnol., (2011) 29:11:1046	22037378